Navigating Antiplatelet Therapy for Thrombosis Prevention 2026

Pathophysiology of Platelet Activation and Thrombus Formation Atherothrombosis remains the primary pathophysiological driver behind acute coronary syndromes (ACS), ischemic cerebrovascular events, and progressive peripheral arterial disease (PAD). Blood platelets small, anucleate cell fragments derived from bone marrow megakaryocytes play a dual role in physiological hemostasis and pathological vascular occlusion. Under baseline conditions, a healthy vascular…